Asymmetrical vertebral growth contributes to scoliosis progression

In the article, “Contributions of Remodeling and Asymmetrical Growth to Vertebral Wedging in a Scoliosis Model“, published in the journal Spine Deformity, researchers at the University of Vermont found in an experimental model that the most significant factor for increased vertebral wedging in younger vertebrae was asymmetrical growth (via the Hueter-Volkmann law), whereas in more mature bone the effect of vertebral body remodeling (Wolff’s law) was more significant.  The authors concluded that the ability to correct vertebral wedging has important implications in nonoperative treatment of scoliosis.  This research supports the importance of brace treatment for scoliosis in children during periods of skeletal growth.